Zapotiltic is a town and municipality in the Southern Region of the state of Jalisco, Mexico. It is located approximately 115 km south of Guadalajara. According to the Population and Housing Count of 2015, the municipality had 29,190 inhabitants. Their name comes from Nahuatl and is interpreted as: "Place of Black Zapotes". It has a territorial extension of 150 km² and its population is mainly dedicated to the tertiary sector.