The Biobío Region is one of the sixteen regions in which the Republic of Chile is divided. Its capital is Concepción. Located in the center of the country, it borders on the north with the Region of Ñuble, on the east with Argentina, on the south with the Region of La Araucanía and on the west with the Pacific Ocean. The region has an area of 23,890.2 km² and a population of 1,557,414 inhabitants, being the third most populated region of the country, behind the Metropolitan regions of Santiago and Valparaíso. The region is composed of the provinces of Arauco, Biobío. And Concepción Its main urban center is the Gran Concepción.
On September 6,2018, the Ñuble province split off from the Biobío Region, becoming the new Ñuble Region.