Alto Demerara-Berbice is one of the 10 administrative regions in which the Republic of Guyana is divided. It delineates the regions of Essequibo-Demerara Occidental, Demerara-Mahaica and Mahaica-Berbice to the north, the East Berbice-Corentyne region to the east, and the Potaro-Siparuni and Cuyuni-Mazaruni regions to the west. Its population in 1991 was 38,598 inhabitants spread over an area of 17,081 km². The current capital is Linden, with other interesting towns such as Ituni, Kalkuni, Kwakwani, Kurupakari, Rockstone and Takama. During the colonial era, the region was divided between the counties of Demerara and Berbice. In 1958 and in 1971 these territories were divided into several regional entities, being in 1980 when the current Alto Demerara-Berbice region was finally established.
It has its own regional assembly, as well as a representative in the National Assembly of Georgetown and two members in the National Congress of the Local Democratic Bodies. Its economy is based mainly on bauxite mines, with many excavations exceeding 80 meters in depth.